Age Reversal
Telomir Pharmaceuticals Co-Founder Frank O’Donnell joined Steve Darling from Proactive to share what the company believe is groundbreaking potential of their new drug designed to extend telomeres, which could reverse aging and age-related diseases. During a recent interview, O'Donnell elaborated on the drug’s potential, supported by extensive research in mice and successful trials in larger animals like a German shepherd.
Drawing from his background in ophthalmology at Johns Hopkins, O'Donnell explained that the drug is developed to fight conditions such as macular degeneration by manipulating telomeres—protective caps on chromosomes that degrade over time. This innovative approach has shifted the company's focus from merely prolonging life to actively reversing signs of aging. O'Donnell also touched on the drug’s promising implications for veterinary medicine, particularly its potential benefits for older dogs suffering from osteoarthritis. Upcoming studies on dogs are planned to further prove the drug's effectiveness before moving to human clinical trials slated to begin in January 2025.
Israeli Scientists Reverse Aging with Hyperbaric Oxygen Therapy
Study finds hyperbaric oxygen treatments halt the aging of blood cells and reverses the aging process.
A new study from Tel Aviv University (TAU) and the Shamir Medical Center in Israel indicates that hyperbaric oxygen treatments (HBOT) in healthy aging adults can stop the aging of blood cells and reverse the aging process. In the biological sense, the adults’ blood cells actually grow younger as the treatments progress.
Shai Efrati reported in Aging - a peer-reviewed journal article published on November 18 that his research team’s 60-day therapy lengthened telomeres, the structures found at the ends of chromosomes, on average by more than a fifth.
He claims this represents a “holy grail” in the battle against aging. However, some other physicians have reservations, and are concerned that he may be opening a Pandora’s box that could end up causing health problems.
“We try to address aging with physical exercise and changes to diet, but this only slows decline,” Efrati told The Times of Israel. “We’re showing that we can actually take the biological clock backwards and improve the quality of blood cells. This means we can start to look at aging as a reversible disease.”
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